Elephant Shark Genome Project
 

Publications:

Ravi, V., Bhatia, S., Gautier, P., Loosli, F., Tay, B.-H., Tay, A., Murdoch, E., Coutinho, P., Heyningen, V. van, Brenner, S., Venkatesh, B. and Kleinjan DA. (2013) Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences. PLoS Genet 9(1): e1003177.   [Fulltext]

Venkatesh, B., Ravi, V., Lee, A.P., Warren, W.C. and Brenner, S. (2013) Basal vertebrates clarify the evolutionary history of ciliopathy-associated genes Tmem138 and Tmem216. Mol. Biol. Evol. 30: 62-65.   [PubMed Access]

Davies, W.I.L., Tay, B-H., Zheng, L., Danks, J.A., Brenner, S., Foster, R.G., Collin, S.P., Hankins, M.W., Venkatesh, B. and Hunt, D.M. (2012) Evolution and Functional Characterisation of Melanopsins in a Deep-Sea Chimaera (Elephant Shark, Callorhinchus milii). PLoS ONE. 7(12): e51276.   [Fulltext]

Tan, Y.Y., Kodzius, R., Tay, B-H., Tay, A., Brenner, S. and Venkatesh, B. (2012) Sequencing and analysis of full-length cDNAs, 5'-ESTs and 3'-ESTs from a cartilaginous fish, the elephant shark (Callorhinchus milii). PLoS ONE. 7(10): e47174.   [Fulltext]

Maeso, I., Irimia, M., Tena, J.J., Gonzalez-Perez, E., Tran, D., Ravi, V., Venkatesh, B., Campuzano, S., Gomez-Skarmeta, J.L. and Garcia-Fernandez, J. (2012) An ancient genomic regulatory block conserved across bilaterians and its dismantling in tetrapods by retrogene replacement. Genome Res. 22 (4): 642-655.   [PubMed Access]

Lane, D.P., Madhumalar, A., Lee, A.P., Tay, B.H., Verma, C., Brenner, S. and Venkatesh, B. (2011) Conservation of all three p53 family members and Mdm2 and Mdm4 in the cartilaginous fish. Cell Cycle. 10 (24): 4272-4279.   [PubMed Access]   [Fulltext]

Lee, A.P., Kerk, S.Y., Tan, Y.Y., Brenner, S. and Venkatesh, B. (2011) Ancient vertebrate conserved noncoding elements have been evolving rapidly in teleost fishes. Mol. Biol. Evol. 28: 1205-1215.   [PubMed Access]

Liu, Y., Ibrahim, A.S., Tay, B.-H., Richardson, S.J., Bell, J., Walker, T.I., Brenner, S., Venkatesh, B. and Danks, J.A. (2010) Parathyroid hormone gene family in a cartilaginous fish, the elephant shark (Callorhinchus milii). J. Bone Miner. Res. 25: 2337-2347.   [PubMed Access]

Inoue, J.G., Miya, M., Lam, K., Tay, B-H., Danks, J.A., Bell, J., Walker, T.I. and Venkatesh, B. (2010) Evolutionary origin and phylogeny of the modern holocephalans (Chondrichthyes: Chimaeriformes): A mitogenomic perspective. Mol. Biol. Evol. 27: 2576-2586.   [PubMed Access]

Tan, Y-P., Li, S., Jiang, X-J., Loh, W., Foo, Y.K., Loh, C-B., Xu, Q., Yuen, W-H., Jones, M., Fu, J., Venkatesh, B. and Yu, W-P. (2010) Regulation of protocadherin gene expression by multiple neuron-restrictive silencer elements scattered in the gene cluster. Nucleic Acids Res. 38: 4985-4997.   [PubMed Access]   [Fulltext]

MacDonald, R.B., Debiais-Thibaud, M., Martin, K., Poitras, L., Tay, B-H., Venkatesh, B. and Ekker, M. (2010) Functional conservation of a forebrain enhancer from the elephant shark (Callorhinchus milii) in zebrafish and mice. BMC Evol. Biol. 10:157.   [PubMed Access]   [Fulltext]

Bajoghli, B., Aghaallaei, N., Hess, I., Rode, I., Netuschil, N., Tay, B.H., Venkatesh, B., Yu, K., Kaltenbach, S.L., Holland, N.D., Diekhoff, D., Happe, C., Schorpp, M. and Boehm, T. (2009) Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates. Cell 138: 186-197.   [PubMed Access]

Davies, W.L., Carvalho, L.S., Tay, B., Brenner, S., Hunt, D.M. and Venkatesh, B. (2009) Into the blue: gene duplication and loss underlie colour vision adaptations in a deep-sea chimaera, the elephant shark Callorhinchus milii. Genome Res. 19: 415-426.   [PubMed Access]   [Fulltext]

Gwee, P.C., Tay, B., Brenner, S. and Venkatesh, B. (2009) Characterization of the neurohypophysial hormone gene loci in elephant shark and the Japanese lamprey: origin of the vertebrate neurohypophysial hormone genes. BMC Evol. Biol. 9: 47. [PubMed Access]   [Fulltext]

Larsson, T.A., Tay, B.H., Sundstrom, G., Fredriksson, R., Brenner, S., Larhammar, D. and Venkatesh, B. (2009) Neuropeptide Y-family peptides and receptors in the elephant shark, Callorhinchus milii confirm gene duplications before the gnathostome radiation. Genomics 93: 254-260.   [PubMed Access]

Ravi, V., Lam, K., Tay, B-H., Tay, A., Brenner, S. and Venkatesh, B. (2009) Elephant shark (Callorhinchus milii) provides insights into the evolution of Hox gene clusters in gnathostomes. Proc. Natl. Acad. Sci. USA. 106: 16327-16332.   [PubMed Access]   [Fulltext]

Wang, J., Lee, A.P., Kodzius, R., Brenner, S. and Venkatesh, B. (2009) Large number of ultraconserved elements were already present in the jawed vertebrate ancestor. Mol. Biol. Evol. 26: 487-490.   [PubMed Access]   [Fulltext]

Ravi, V. and Venkatesh, B. (2008) Rapidly evolving fish genomes and teleost diversity. Curr. Opin. Genet. Dev. 18: 544-550. [PubMed Access]

Yu, W.P., Rajasegaran, V., Yew, K., Loh, W., Tay, B.H., Amemiya, C.T., Brenner, S. and Venkatesh, B. (2008) Elephant shark sequence reveals unique insights into the evolutionary history of vertebrate genes: a comparative analysis of the protocadherin cluster. Proc. Natl. Acad. Sci. USA. 105: 3819-3824.   [PubMed Access]   [Fulltext]

Venkatesh, B., Kirkness, E.F., Loh, Y.H., Halpern, A.L., Lee, A.P., Johnson, J., Dandona, N., Viswanathan, L.D., Tay, A., Venter, J.C., Strausberg, R.L. and Brenner, S. (2007) Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome. PLoS Biol. 5(4): e101.   [PubMed Access]   [Fulltext]

Venkatesh, B., Kirkness, E.F., Loh, Y.H., Halpern, A.L., Lee, A.P., Johnson, J., Dandona, N., Viswanathan, L.D., Tay, A., Venter, J.C., Strausberg, R.L. and Brenner, S. (2006) Ancient noncoding elements conserved in the human genome. Science 314: 1892.   [PubMed Access]

Venkatesh, B., Tay, A., Dandona, N., Patil, J.G. and Brenner, S. (2005) A compact cartilaginous fish model genome. Curr. Biol. 15: R82-R83.   [PubMed Access]


Comparative Genomics Lab, IMCB  

Queries to: eshark at imcb.a-star.edu.sg